|
|
|
Binding partners/contacts |
|
|
MDD |
Function |
Core
components |
Specific
components |
|
MDB1 |
Repression |
Non-HDAC1 deacetylase |
|
|
MDB2a |
Repression |
HDAC1/2, RbAP46/48 |
?Mi2/NuRD:Mi2b,MTA-2 |
|
MDB2b |
Putative demethylase/repression |
|
|
|
MDB3 |
Repression |
HDAC1/2, RbAP46/48 |
Mi2/NuRD: Mi2b, MTA-2 |
|
MDB4 |
DNA repair |
|
|
|
MeCP2 |
Repression |
HDAC1/2, RbAP46/48 |
Sin3A, SAP30, SAP18 |
HDAC1 and HDAC2 – histone de-acetylases
RbAp46, RbAp48 – histone-binding proteins